Reactive Oxygen Species (ROS)-Responsive Tellurium-Containing Hyperbranched Polymer

Ruochen Fang, Huaping Xu, Wei Cao, Liulin Yang and Xi Zhang

Polym. Chem., 20156, 2817-2821.

Materials responsive to reactive oxygen species (ROS) at a physiological level are of great significance in diagnostic and therapeutic applications. We have synthesized a water-soluble tellurium-containing hyperbranched polymer and demonstrated that it forms a kind of ROS-responsive aggregate. In aqueous environment, the polymer aggregates can swell under biologically relevant concentration of H2O2, which could be expected to find applications in fields such as elimination of excess ROS.

Fang R. Polym Chem