Selenium-containing Coordinating Assemblies with Selective Anti-cancer Activity: the Control of Reactive Oxygen Species.

Tianyu Li, Yu Yi and Huaping Xu

Acta Chim. Sinica, 2014, 72, 1079-1084.

Coordinating assemblies was prepared via coordination between selenium-containing molecules and platinum-containing compounds. These assemblies can induce higher concentration of ROS in cancer cells than in normal cells, thus raising selective anti-cancer activity. This work broadens the applications of simple platinum-containing compounds and selenium-containing molecules in the field of cancer treatment, also develops a new route for preparation of selective anti-cancer drugs.

Li TY 2014