Author: wanglu
Biomaterials, 2019, 225, 119514.
Angew. Chem. Int. Ed., 2020, 132, 2722.
Adv. Mater.; 2020, 32, 1907569.
Adv. Mater.; 2020, 32, 1907568.
CCS Chem.; 2020, 2, 225–235.
Biomaterials; 2020, 249, 120054.
Adv. Sustainable Syst.; 2020, DOI: 10.1002/adsu.202000072.
Joint Group Meeting between Prof. Huaping Xu’s Group and Prof. Jintao Zhu’s Group
On May 11th, an online joint group meeting was held between Prof. Huaping Xu’s Group from Tsinghua University and Prof. Jintao Zhu’s Group from Huazhong University of Science and Technology.
The meeting was organized by Mr. Cheng Liu from Xu’s Group and Mr. Shuo Du from Zhu’s Group and chaired by Mr. Banruo Xianyu from Xu’s Group and Mr. Shuo Du from Zhu’s Group.
Mr. Pei Liu from Zhu’s Group made an oral presentation entitled “Polymer microneedles with interconnected porous structures via phase inversion route for transdermal medical applications”.
Dr. Jiahao Xia from Xu’s Gro...
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Anti-recurrence/Metastasis and Chemosensitization Therapy with Thioredoxin Reductase-interfering Drug Delivery System
Jichun Yang, Shuojiong Pan, Shiqian Gao, Yiheng Dai, Huaping Xu
Biomaterials; 2020, 249, 120054.
Thioredoxin reductase (TrxR) is an essential mammalian enzyme that possesses a selenocysteine active site. TrxR is overexpressed in many malignant tumors and has a close relationship with apoptosis, drug resistance, recurrence and metastasis of tumors. Recently, TrxR has emerged as a promising target for anticancer therapy. Herein, we developed a TrxR-interfering drug delivery system (DDS) based on RGD-PEG-PUSeSe-PEG-RGD self-assembling micelles for imaging-guided gemcitabine (GEM) chemosensiti...
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