Wei Chen; Ruotong Deng; Yang Cheng; Wei Cao* ; Huaping Xu*
Acc. Chem. Res. 2026
Selenium is an essential element widely utilized across biological systems, where it imparts unique chemical functionality to biomacromolecules. While selenoproteins are well appreciated in humans, other selenium-containing biomacromolecules remain largely absent, and the development of selenium-based therapeutics has lagged. Here, from the perspective of molecular design, we introduce a series of selenium-containing polymers with diverse molecular structures and elucidate their in vivo effect, aiming to advance...
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Author: wanglu
Visible Light Driven Diselenide Chemistry for Simultaneous 3D Patterning and Mechanical Reinforcement
Jianbing Liu, Chaowei He, Peng Zhao, Yizheng Tan*, Huaping Xu*
Chemistry – A European Journal , 2026: e71812.
Three-dimensional (3D) patterning on polymer surfaces is typically achieved by photolithography or related techniques, which often involve complex procedures, high-energy ultraviolet light, and risk of material damage. Here, we report a visible light-driven strategy that exploits the dual functionality of stress relaxation via dynamic bond exchange and radical-initiated polymerization to create raised 3D patterns on diselenide-containing polyurethane films. Under mild visible light i...
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Prof. Robert L.Z. Hoye visited our group and gave a lecture.
On August 5th, 2026, Prof. Robert L.Z. Hoye from the University of Oxford delivered an academic lecture entitled “Perovskite-Inspired Materials for Energy Harvesting and Healthcare: Critical Role of Electron-Phonon Coupling” .
Robert Hoye is an Associate Professor of Materials Chemistry atthe University of Oxford, where he is also a Fellow of St. John'sCollege and a Royal Academy of Engineering Senior Research Fellow.Prof. Hoye completed his PhD at the University of Cambridge (2012-2014), followed by a postdoc at MIT (2015-2016). In 2022, he movedto Oxford as Associate Professor. His group fo...
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Bifunctional injectable selenium-containing polyurethane hydrogels for periodontal regeneration through endoplasmic reticulum stress modulation
Mingchu Zhao, Mo Zhai, Zhuoxin Ge, Xiaodong Guo, Zhuqing Wan, Xiaoqiang Bai, Huaping Xu*, Yongsheng Zhou*, Longwei Lv*
BMEMat 2026, e70105.
Periodontitis causes progressive destruction of both periodontal soft and hard tissues, leading to tooth loss and functional impairment. Conventional treatments, such as mechanical debridement and antibiotic therapy, are often insufficient for effective regeneration due to persistent local inflammation and the complex architecture of gingival and alveolar bone defects. In this study, we developed a thermo-responsive, injectable hydrogel composed of hydro...
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Redox-regulated fusion and fission of Se/Te-containing polymer assemblies for compartmentalized reactions
Zhuoxin Ge, Muqing Cao*, Huaping Xu*
Polym. Chem. 2026; 17 (28): 3098
The fusion and fission of cellular membranes are fundamental dynamic processes in living systems, the precise regulation of which largely depends on the redox microenvironment. Constructing biomimetic model systems capable of reversible regulation under mild conditions is of great significance for understanding membrane dynamics. In this work, a class of amphiphilic block copolymers containing selenium/tellurium (Se/Te) motifs was designed and synthesized, which can self-assemble in aqueous solution into stable nanostructu...
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Prof. Omar F. Mohammed visited our group and gave a lecture.
On July 10, 2026, Professor Omar F. Mohammed from King Abdullah University of Science and Technology delivered an academic lecture entitled “Glassy X-ray Imaging Scintillators: From Laboratory Discovery to Market Translation” .
Professor Mohammed is a Professor at KAUST. His research focuses on advanced optoelectronic materials and devices, including solar cells, light-emitting diodes, and X-ray imaging scintillators, supported by ultrafast laser spectroscopy, 4D electron imaging, and computational materials science.
In his lecture, Professor Mohammed introduced recent advances in glassy sci...
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Nobel Laureate Jean-Marie Lehn Delivered a Lecture
On July 9, 2026, Nobel Laureate in Chemistry Professor Jean-Marie Lehn delivered a lecture entitled “Perspectives in Chemistry: Molecular – Supramolecular – Adaptive Chemistry” . Invited by Professors Xi Zhang and Huaping Xu, the lecture was the seventh session of the Department’s Centennial Academic Forum.
Professor Lehn reviewed the evolution of chemistry from molecular chemistry to supramolecular and adaptive chemistry. He first highlighted how molecular chemistry enables the construction of increasingly complex molecules through precise control of covalent bonds. He then introduced supram...
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Prof. Jonathan Nitschke visited our group and gave a lecture.
On June 11th, 2026, Prof. Jonathan Nitschke from the University of Cambridge visited our group and delivered a lecture on his research.
Prof. Jonathan Nitschke received his bachelor's degree from Williams College (USA) in 1995 and his doctorate from the University of California, Berkeley in 2001 under the supervision of T. DonTilley. He then undertook postdoctoral studies with Jean-MarieLehn in Strasbourg under the auspices of a US NSF fellowship, and in 2003 he started his independent research career as a Maitre-assistant (fixed-term independent PI) in the Organic Chemistry Department of the...
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Polymer Shape Morphing Based on Dynamic Chemistries
Muqing Cao, Yizheng Tan*, Huaping Xu*
ACS Appl. Mater. Interfaces, 2026, 18, 19, 27128
Shape morphing materials possess an enhanced adaptability to diverse environments while minimizing material usage and energy consumption. The main challenge in this area lies in applying the driving force and stimuli in a rapid, precise, and cost-effective manner to enhance the efficiency of mass production with more variety, lower cost, and better sustainability. This perspective summarizes methods and strategies developed recently for polymer shape morphing via dynamic chemistries, from the traditional m...
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Congratulations! Prof. Huaping Xu has been admitted as a Fellow of the Chinese Chemical Society!
In April 2026, Prof. Huaping Xu was admitted as a Fellow of the Chinese Chemical Society (FCCS).
Fellow is the highest membership grade of the Chinese Chemical Society, awarded to distinguished members who have made systematic and creative achievements as well as significant contributions to chemistry and related fields. Since the establishment of the Fellow system in 2019, no more than 50 Fellows have been elected each year, and there are 346 Fellows to date.
Warm congratulations to Prof. Xu!
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