Gamma radiation responsive side-chain tellurium-containing polymer for cancer therapy

Fuqiang Fan, Shiqian Gao, Shaobo Ji, Yu Fu, Pengpeng Zhang and Huaping Xu  Mater. Chem. Front., 2018, 2, 2109-2115 The combination of chemotherapy and radiotherapy could not only enhances cancer treatment efficacy, but also shortens the period of the overall treatment and relieves the negative emotions of the patients during the remedy. Here, we presented a novel strategy for coordinating the chemotherapy drug CDDP with a tellurium-containing polymer, which restrained the tumour cytotoxicity of these two portions. After low dose γ-radiation, CDDP departed from the coordination complexes, and...
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Non-metal-Heteroatom-Doped Carbon dots: Synthesis and Property

Feng Li, Dayong Yang and Huaping Xu Chem. Eur. J., 2019, 25, 1165-1176 Carbon dots (CDs) are new materials with capability in bioimaging, optical device, catalysis, and many other fields. Their advantages, such as ease of large‐scale preparation, low cost of precursor, highly tunable photoluminescence, satisfactory biocompatibility, and photostability against photobleaching, make them competitive alternatives to conventional semiconductor‐based quantum dots and organic dyes. In order to overwhelm other luminescent materials in applications, their functionalities are still needed to impro...
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Xu group attended the 31st CCS Congress

31st CCS Congress
On Mar. 5th – 8th 2018, Prof. Huaping Xu and Lu Wang, Tianyu Li, Jiahao Xia, Chenxing Sun and Cheng Liu attended the 31st CCS Congress held in Hangzhou, Zhejiang. Prof. Huaping Xu gave an invited presentation of “Dynamic Chemistry of Selenium” on Mar. 6th. Lu Wang gave poster presentation on Mar. 6th. Tianyu Li, Jiahao Xia and Chenxing Sun gave poster presentation on Mar. 7th, respectively. Lu Wang received “Best Poster Award”.
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Joint group meeting with Huo’s group

WechatIMG305
On Mar. 31st, 2018, Xu's group and Prof. Fengwei Huo's group held a joint group meeting in Nanjing Tech University, Nanjing. At the meeting, five students from each group gave presentations. Students from Xu's group introduced dynamic chemistry and responsive systems, students from Huo's group introduced metal-organic framework and flexible electronic devices.  
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Highly Fluorescent Chiral N-S-Doped Carbon Dots from Cysteine: Affecting Cellular Energy Metabolism

Feng Li, Yiye Li, Xiao Yang, Xuexiang Han, Yang Jiao, Taotao Wei, Dayong Yang, Huaping Xu and Guangjun Nie Angew. Chem. Int. Ed., 2018, 57, 2377-2382 Cysteine-based chiral optically active carbon dots (CDs) and their effects on cellular energy metabolism, which is vital for essential cellular functions, have been barely reported. A green and effective synthesis strategy for chiral N-S-doped CDs (fluorescence quantum yield ca. 41.26 %) based on hydrothermal treatment of lord-cysteine at as low as 60℃ has been developed. This suggested that cysteine was instable in aqueous solutions and ac...
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