Lu Wang, Wencong Wang, Wei Cao and Huaping Xu Polym. Chem., 2017, 8, 4520–4527 Nanomaterials with hierarchical responsiveness are of great significance for not only fundamental science but also future biomedical applications due to sophisticated and hierarchical physiological environments. Here, we report a selenium- and tellurium-containing block copolymer that can be stepwise oxidized by both chemical methods and electrochemical methods. Differences in sensitivity to the oxidation of selenium and tellurium were employed. By tuning the concentration of the oxidant and ...

Jiahao Xia, Feng Li, Shaobo Ji and Huaping Xu ACS Appl. Mater. Interfaces, 2017, 9, 21413−21421 Graphene oxide (GO) is an important two-dimensional material since it is water soluble and can be functionalized to adapt to different applications. However, the current covalent functionalization methods usually require hash conditions, long duration and sometimes even multi-steps, while noncovalent functionalization is inevitably unstable, especially under physiological environment where competing species exist. Diselenide bond is a dynamic covalent bond and can respond t...

Weiqiang Zhou, Hongfeng Li, Bin Xia, Wenlan Ji, Shaobo Ji, Weina Zhang, Wei Huang, Fengwei Huo and Huaping Xu Nano Res., 2018, 11, 5761-5768 The development of artificial enzyme mimics has been rapidly growing and attracting more and more attention owing to their remarkable advantages over natural enzymes. Herein, we developed a general and facile method to fabricate an efficient glutathione peroxidase (GPx) mimic by grafting the selenium-containing molecule (phenylselenylbromide: PhSeBr) to the framework of Zr(IV)-based UiO-66-NH2 (UiO-66-Se). With glutathione (GSH) serving as the substrate...