Prof. Huaping Xu co-organized “Beijing Symposium 2017: Polymeric Biomaterials”

Posted on November 3, 2017 by wanglu

Together with Prof. Hong Chen and Prof. Zhuang Liu, Prof. Huaping Xu co-organized a NSFC supported Forum “Beijing Symposium 2017: Polymeric Biomaterials” during October 29-31, 2017 at Soochow University, Suzhou, China. The main goal of this symposium is to provide the opportunity for young scientists of polymeric biomaterials (30 in total from around the world) to know each other for future collaborations.

Visible Light-Induced Plasticity of Shape Memory Polymers

Posted on October 21, 2017 by wanglu

Shaobo Ji, Fuqiang Fan, Chenxing Sun, Ying Yu and Huaping Xu ACS Appl. Mater. Interfaces, 2017, 9, 33169-33175 Plasticity of thermoset polymers has been realized by introducing exchangeable bonds, and the plasticity is mostly triggered via heat or UV light. Visible light is a relatively mild trigger that has not been used to induce plasticity in polymer materials. Herein, thermoset polyurethanes (PUs) containing diselenide bonds are fabricated that possess visible light-induced plasticity along with shape memory behavior. A series of PUs with different diselenide bond contents were teste...

Selenium-Doped Carbon Quantum Dots for Free-Radical Scavenging

Posted on October 21, 2017December 7, 2017 by wanglu

Feng Li, Tianyu Li, Chenxing Sun, Jiahao Xia, Yang Jiao and Huaping Xu Angew.Chem. Int.Ed., 2017, 56, 9910–9914 Heteroatom doping is an effective way to adjust the fluorescent properties of carbon quantum dots. However, selenium-doped carbon dots have rarely been reported, eve though selenium has unique chemical properties such as redox-responsive properties owing to its special electronegativity. Herein, a facile and high-output strategy to fabricate selenium- doped carbon quantum dots (Se-CQDs) with green fluorescence (quantum yield 7.6 %) is developed through the hydro-thermal treatment...

Xu group attended the 2017 Annual National Polymer Congress

Posted on October 18, 2017October 18, 2017 by wanglu

Oct. 10th – 14th 2017, Prof. Huaping Xu and Shaobo Ji, Tianyu Li, Jiahao Xia, Fuqiang Fan, Chenxing Sun and Wentian Xiang attended the 2017 Annual National Polymer Congress held in Chengdu, Sichuan. Prof. Huaping Xu gave an invited presentation of "Newly Designed Construction of Modern Polymer Chemistry Experimental Course" on Oct. 13th and an oral presentation of “ROS-responsive Tellurium-containing Polymers” on Oct. 12th. Shaobo Ji, Tianyu Li, Jiahao Xia, Fuqiang Fan and Chenxing Sun gave poster presentation on Oct. 11th, respectively. Tianyu Li and Jiahao Xia received “Best Poster ...

Prof. Bradley Olsen visited Tsinghua University and gave a lecture

Posted on September 15, 2017October 16, 2017 by wanglu

On Sep. 14th, 2017, Prof. Bradley Olsen from Massachusetts Institute of Technology, USA visited Tsinghua University and gave a lecture about “Revisiting the Physical Chemistry of Polymer Networks”. In the morning, Shaobo Ji, Tianyu Li and Jiahao Xia introduced their work to Prof. Bradley Olsen, respectively.

ACIE, 2014, 53, 6781

Posted on August 18, 2017 by wanglu

Nanomedicine Assembled by Coordinated Selenium-Platinum Complexes Can Selectively Induce Cytotoxicity in Cancer Cells by Targeting the Glutathione Antioxidant Defense System

Posted on August 14, 2017June 12, 2018 by wanglu

Feng Li, Tianyu Li, Xuexiang Han, Hao Zhuang, Guangjun Nie, and Huaping Xu ACS BIOMATER-SCI ENG, 2018, 4, 1954-1962 Selenium is a unique, essential trace element that plays an important role in the antioxidant defense and redox regulation of biological processes. We have reported that novel selenium-containing platinum-based anticancer molecules (EG-Se/Pt) had selective cytotoxicity toward cancer cells. Herein, we found the underlying mechanism of selective cytotoxicity to be closely related to the glutathione antioxidant defense system. Elevated ROS make cancer cells more vulnerable to ...

Multi-hierarchical Responsive Polymers: Stepwise Oxidation of a Selenium- and Tellurium-Containing Block Copolymer with Sensitivity to both Chemical and Electrochemical Stimuli

Posted on July 5, 2017October 21, 2017 by wanglu

Lu Wang, Wencong Wang, Wei Cao and Huaping Xu Polym. Chem., 2017, 8, 4520–4527 Nanomaterials with hierarchical responsiveness are of great significance for not only fundamental science but also future biomedical applications due to sophisticated and hierarchical physiological environments. Here, we report a selenium- and tellurium-containing block copolymer that can be stepwise oxidized by both chemical methods and electrochemical methods. Differences in sensitivity to the oxidation of selenium and tellurium were employed. By tuning the concentration of the oxidant and ...

Selenium-functionalized Graphene Oxide that Can Modulate the Balance of Reactive Oxygen Species

Posted on June 7, 2017July 11, 2017 by wanglu

Jiahao Xia, Feng Li, Shaobo Ji and Huaping Xu ACS Appl. Mater. Interfaces, 2017, 9, 21413−21421 Graphene oxide (GO) is an important two-dimensional material since it is water soluble and can be functionalized to adapt to different applications. However, the current covalent functionalization methods usually require hash conditions, long duration and sometimes even multi-steps, while noncovalent functionalization is inevitably unstable, especially under physiological environment where competing species exist. Diselenide bond is a dynamic covalent bond and can respond t...

Prof. Weibo Cai visited Tsinghua University and gave a lecture

Posted on May 22, 2017May 22, 2017 by wanglu

On May 16th, 2017, Prof. Weibo Cai from University of Wisconsin - Madison, USA visited Tsinghua University and gave a lecture about “Molecular Imaging, Imaging-Guided Drug Delivery, and Theranostics”.