Banruo Xianyu, Shuojiong Pan, Shiqian Gao, Huaping Xu*, Tianyu Li* Small, 2023, 2306225. The blockade of immune checkpoints has emerged as a promising strategy for cancer immunotherapy. However, most of the current approaches focus on T cells, leaving natural killer (NK) cell-mediated therapeutic strategies rarely explored. Here, a selenium-containing nanocomplex is developed that acts as a dual immune checkpoint inhibitor to reinvigorate NK cell-based cancer immunotherapy. The Se nanocomplex can deliver and release siRNA that targets programmed death ligand-1 (PD-L1) in tumor cells, there...

Yizheng Tan, Jun Guan, Huaping Xu* Matter; 2023, 6, 3121. A hyper-stable cholesteric heliconical superstructure has been achieved at room temperature through a simple strategy of mixing liquid crystal dimers. This breakthrough, recently reported in Matter by Li and colleagues, demonstrates an unprecedented and practical optic system for monochromatic light filtering important for various fields.

Ningyue Chen, Shuwei Li, Peng Zhao, Ran Liu, Yu Xie, Jin-Liang Lin, Christian A. Nijhuis, Bingqian Xu, Liang Zhang*, Huaping Xu*, Yuan Li* Sci. Adv.; 2023, 9, eadh3412. The molecular electronic devices based on self-assembled monolayer (SAM) on metal surfaces demonstrate novel electronic functions for device minimization yet are unable to realize in practical applications, due to their instability against oxidation of the sulfur-metal bond. This paper describes an alternative to the thiolate anchoring group to form stable SAMs on gold by selenides anchoring group. Because of the formation of...