Shuojiong Pan, Jun Guan, Banruo Xianyu, Yizheng Tan, Tianyu Li, and Huaping Xu
Adv. Mater.; 2023, 23, 2211370.
As a specialized immune effector cell, natural killer (NK) cells play a very important role in immunotherapy, but tumor immunosuppression caused by abnormal expression of cancer cells seriously weakens its therapeutic effect and leads to exhaustion. Here, we developed a self-assembled selenium containing nanoparticles (NPs) composed of Cetuximab, C5SeSeC5 and inhibitor LY345899 to reverse NK cell exhaustion. The obtained NPs can target EGFR on the surface of cancer cells and locat...
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Author: wanglu
Mechanochemistry of dynamic chalcogen-containing polymers: a minireview
Muqing Cao, Yizheng Tan and Huaping Xu
New Journal of Chemistry; 2023, 47, 5582.
In recent years, mechanochemistry of polymers, which means the reactivity of polymers under mechanical stimuli, has been widely studied and greatly developed. Among various kinds of mechano-responsive polymers, dynamic chalcogen-containing polymers have attracted more attention due to their sensitive responsiveness and precise biofunction. In this perspective, we provide an overview of mechanochemistry of dynamic chalcogen-containing polymers, including both fundamental mechanochemistry and applications. Particu...
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The 4th Table Tennis Tournament of Xu’s Group
On Feb. 12th, 2023, the 4th Table Tennis Tournament of Xu's Group was held in Gas Film Hall, Tsinghua University, with 15 group members joining in.
Mr. Jinyan Si and Mr. Zhuoxin Ge advanced to the final round. And finally, Mr. Jinyan Si won the championship of this year's tournament.
Keep positive in both exercise, work and life!
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Happy New Year！
Scholarships and prizes of Xu’s group in 2022
Dynamic Fluorescent Patterning Based on Visible-Light-Responsive Diselenide Metathesis
Jinyan Si, Peng Zhao, Jun Guan, Shaobo Ji and Huaping xu
Langmuir; 2022, 38, 13272
A diselenide bond, as a dynamic covalent bond, is a versatile tool to construct smart interfaces, which can respond to visible light. In this work, we used microcontact printing (μCP) to construct diselenide patterns on quartz substrates. Fluorescent patterns were obtained on the modified surfaces via the visible-light-induced diselenide metathesis reaction, which allowed the patterning process to be fast, dynamically erasable, and compatible with different fluorescent molecules including rhodamine B and b...
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Congratulations！Our alumni Dr. Wei Cao and Dr. Shaobo Ji start their academic career！
Our alumni Dr. Wei Cao and Dr. Shaobo Ji started their academic career！Recently they joined Beijing Normal University and Soochow University respectively.
Congratulations and best wishes for their future!
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Rapidly reprogrammable actuation of liquid crystal elastomers
Cheng Liu, Shaobo Ji and Huaping Xu
Matter; 2022, 3, 2397.
A rapid and reprogrammable alignment strategy for the reversible actuation of liquid crystal elastomers has been achieved through the phase-transition-induced shape memory effect. This breakthrough, recently reported in Advanced Materials by Xie and colleagues, illustrated the important role of shape-memory-induced stress regulation in developing and improving functional polymer materials.
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Thermal- and Light-driven Metathesis Reactions Between Different Diselenides
Xiaoying Kang, Yuan Yuan, Huaping Xu and Yulan Chen
Chem. Res. Chinese Universities, 2022, 38, 516.
Thermal- and light-driven diselenide metathesis reactions with different types of diselenides are investigated systematically. Their exchange reaction rates and equilibrium conversions are compared in the aspects of the different diselenide structures, activation conditions and solvents. As a result, the metathesis reactions between diselenide small molecules are demonstrated with high dynamic and sensitive features, which can be broadly tuned by varying the electron affinity and aromaticity o...
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Water-Enhanced and Remote Self-Healing Elastomers in Various Harsh Environments
Peng Zhao, Muqing Cao, Cheng Liu, Yiheng Dai, Yizheng Tan, Shaobo Ji, and Huaping Xu
ACS Appl. Mater. Interfaces.; 2022, 14, 27413.
The development of underwater remote stimulus-responsive self-healing polymer materials for applications in inaccessible and urgent situations is very challenging because water can readily disturb traditional noncovalent bonds and absorb heat, UV light, IR light, and electromagnetic wave energy at the wave band of micrometers and millimeters. Herein, visible-light-responsive diselenide bonds are employed as the healing moieties to produce a water-enhanced and re...
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