Tellurium-containing Nanoparticles for Controlled Delivery of Cisplatin Based on Coordination Interaction

Wei Cao, Feng Li, Ruofan Chen and Huaping Xu RSC Adv., 2016, 6, 94033-94037. Tellurium containing nanoparticles were designed and synthesized for the delivery of cisplatin based on coordination interaction. The tellurium containing nanomedicine could achieve betterin vivo efficacy and reduce side effects, owing to the prolonged blood circulation. This kind of approach marked a new frontier of tellurium containing nanomedicine.  
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Selenium-containing Amphiphiles Reduced and Stabilized Gold Nanoparticles: Kill Cancer Cells via Reactive Oxygen Species

Tianyu Li, Feng Li, Wentian Xiang, Yu Yi, Yuyan Chen, Liang Cheng, Zhuang Liu and Huaping Xu ACS Appl. Mater. Interfaces, 2016, 8, 22106–22112. Selenium has attracted increasing interest in the past decades because of the function of regulating the redox balance in human body. However, biomedical studies of selenium are still limited. Gold nanoparticles (AuNPs), typically prepared by a first reduction step followed by a second stabilization step, are widely applied in biomedical studies. But their own anti-cancer activity is less studied. Here, we report 2-nm AuNPs with significant anti-...
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Stimuli-Responsive Layer-by-Layer Tellurium-Containing Polymer Films for the Combination of Chemotherapy and Photodynamic Therapy

Fuqiang Fan, Lu Wang, Feng Li, Yu Fu and Huaping Xu ACS Appl. Mater. Interfaces, 2016, 8, 17004-17010. Tellurium-containing photoresponsive polyelectrolyte multilayer films were fabricated by layer-by-layer assembly of a tellurium-containing polymer, photosensitizer, and poly(styrenesulfonate). The resulting films were investigated by UV/vis spectroscopy, XPS, EPR, and fluorescence spectroscopy. Under visible light, the photosensitizer in the film is excited and transforms triplet oxygen into singlet oxygen in aqueous solution. Singlet oxygen oxidizes −Te– to high valence state (Te═O) on...
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Prof. Huaping Xu attended the 30th CCS Congress

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Jul. 1st – 4th 2016, Prof. Huaping Xu and his students Shaobo Ji, Lu Wang, Tianyu Li, Jiahao Xia, Weiqiang Zhou and Fuqiang Fan attended the 30th CCS Congress held in Dalian, Liaoning . Prof. Huaping Xu gave an invited presentation of "Responsive self-assemblies of Te-containing polymers" on Jul. 3rd. Shaobo Ji, Lu Wang, Tianyu Li,  Weiqiang Zhou and Fuqiang Fan gave poster presentation on Jul. 4th, respectively.
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Tellurium-Containing Polymers: Towards Biomaterials and Optoelectronic Materials

Lu Wang, Wei Cao and Huaping Xu ChemNanoMat, 2016, 2, 479-488. Tellurium-containing polymers have been increasingly attractive owing to their unique properties as biomaterials and optoelectronic material. The relatively large atom size and low electronegativity of tellurium give tellurium many unique properties, such as coordination ability and redox sensitivity. Introducing of tellurium can endow materials different responsiveness, which makes them possible to be employed as biomaterials. The narrow band gap of polytellurophene also makes it possible to be used in optoelectronic materia...
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