Weiqiang Zhou, Lu Wang, Feng Li, Weina Zhang, Wei Huang, Fengwei Huo and Huaping Xu Adv. Funct. Mater., 2017, 27, 1605465. The development of efficient multi-responsive drug delivery systems (DDS) to control drug release has been widely explored. Herein, we report a facile strategy that enabled the micelles of the selenium-containing polymer with the drug to be encapsulated in metal-organic frameworks (MOFs), which served as multi-responsive drug release by employing the selenium-containing polymers with redox-triggered property and the MOFs with pH-triggered property in DDS. In this cas...

Jiahao Xia, Shaobo Ji and Huaping Xu Polym. Chem., 2016, 7, 6708-6713. We demonstrated the proof-of-concept that diselenide dynamic chemistry can perform at oil/water interface. The assymetric diselenide-containing polymer, which would decompose under visible light once seperated from metathesis mixture, was successfully stabilized via a micelle induced stabilization method.

Wei Cao, Feng Li, Ruofan Chen and Huaping Xu RSC Adv., 2016, 6, 94033-94037. Tellurium containing nanoparticles were designed and synthesized for the delivery of cisplatin based on coordination interaction. The tellurium containing nanomedicine could achieve betterin vivo efficacy and reduce side effects, owing to the prolonged blood circulation. This kind of approach marked a new frontier of tellurium containing nanomedicine.