Ruotong Deng, Wei Chen, Hanjie Zhu, Yuxi Li, Yining Ou, Jian Wang, Qing Ruan, Xuanying Zhang, Junbo Zhang, Yongxian Zhang, Yantao Niu, Zhubin Hu, Chunlei Zhang, Huaping Xu*, Wei Cao* Nat Commun.; 2025, 16, 7895 The escalating utilization of ionizing radiation across medicine and industry underscored the paramount urgency of effective radioprotective materials. Conventional materials such as lead and concrete are widely used, and lead-free materials have also emerged to solve the problems of cumbersome and toxic lead, such as metal-containing micro/nano materials and polymers. Nevertheless, t...

Ruihao Zhou, Muqing Cao, Yizheng Tan*, Mark Neisser*, Huaping Xu* Sci. Adv.; 2025, 11, eadx1918 Extreme ultraviolet (EUV) lithography has become the essence of advanced semiconductor manufacturing processes. While enabling smaller feature sizes, EUV lithography imposes increasingly stringent requirements on the comprehensive performance and stochastic defect suppression of photoresist. The widely recognized strategy to minimize these defects is a material that integrates high EUV absorption and energy utilization into a homogeneous system based on molecular building blocks—the ideal formul...

Jichun Yang*, Yuhan Wang, Kang Wang, Xiaohui Chen, Yilin Liu, Qianqian Wu, Hengyi Chen, Guangchao Qing, Yunqian Fu, Xin Cui, Yao Luo, Sitong Wang. Guoliang Duan. Mingyang Zhang. Yimin Jia. Xinghong Hu, Zhizeng Wang, Xing-Jie Liang*, Huaping Xu*. Yang Luo*. ACS Nano, 2025, 19, 31183. Cancer is one of the most commonly diagnosed diseases with high mortality, and approximately 50% of patients are prone to present metastasis after various treatments. The shedding of circulating tumor cells (CTCs) during tumor therapy is the root cause of metastasis. In this work, we proposed a focused antimetast...

Mo Zhai, Zilun Huang, Banruo Xianyu, Xiaoqiang Bai, Zhuqing Wan, Yang Fu, Huaping Xu*, Longwei Lv*, Yongsheng Zhou* Aggregate; 2025, 0:e70074 Diabetic wound healing impairment, a common complication of diabetes, has limited clinical treatment options and poor therapeutic outcomes, causing significant physical pain and psychological burden for patients. This study aims to accelerate wound healing by modulating cellular stress responses, offering a safe and efficient new therapeutic strategy. Herein, a selenium-containing polyurethane (SePU) thermo-sensitive hydrogel was synthesized, and its...

Jun Guan, Ruihao Zhou, Hengxue Shi, Shenghan Zhang, Chaowei He, Muqing Cao, Lei Jiao*, Huaping Xu* Chem Catalysis; 2025, 5, 101429 Carboradical reservoirs are non-radical precursors that controllably release stored radicals to directly participate in product formation, making them critically important in organic chemistry. However, no aryl radical reservoir has been reported to date. Here, we have constructed an aryl radical reservoir via polytelluroxane (PTeO)-mediated activation of arylboronic acids under white light. PTeO, featuring an inorganic Te–O backbone with organic side chains, f...

Jinyan Si, Chaowei He and Huaping Xu* ACS Appl. Mater. Interfaces; 2025, 17, 37090 Strain isolation strategies are widely employed in flexible electronic device fabrication to enhance their stretchability. One common approach involves modulating the cross-linking degree of the materials to create regions with a heterogeneous modulus. However, existing materials typically rely on permanent cross-linking networks, which restrict their recyclability and environmental degradability. In this study, we introduce a recyclable thermosetting tellurium-containing polyurethane (TeHPU) as a substrate ...

Chengfei Liu, Yifan Jin, Jiahui Ma, Wei Tian*, Huaping Xu* Chinese J. Polym. Sci.; 2025, 10.1007/s10118-025-3341-7 Intracellular polymerization is an emerging field, showcasing high diversity and efficiency of chemistry. Motivated by the principles of natural biomolecular synthesis, polymerization within living cells is believed to be a powerful and versatile tool to modulate cell behavior. In this review, we summarized recent advances and future trends in the field of intracellular polymerization, specifically focusing on covalent and supramolecular polymerization. This discussion comprehen...