Chengfei Liu, Banruo Xianyu, Yiheng Dai, Shuojiong Pan, Tianyu Li, and Huaping Xu*
ACS Nano; 2023, 17, 11905.
Polymerization inside living cells provides chemists with a multitude of possibilities to modulate cell activities. Considering the advantages of hyperbranched polymers, such as a large surface area for target sites and multilevel branched structures for resistance to the efflux effect, we reported a hyperbranched polymerization in living cells based on the oxidative polymerization of organotellurides and intracellular redox environment. The intracellular hyperbranched polymerizati...
More
Author: wanglu
Tellurium-containing Polymers: Recent Developments and Trends
Yiheng Dai, Jun Guan, Shenghan Zhang, Shuojiong Pan, Banruo Xianyu, Zhuoxin Ge, Jinyan Si, Chaowei He, Huaping Xu
Prog. Polym. Sci.; 2023, 141, 101678.
Significant progresses have been made in tellurium-containing polymers over the past decades. Just like other heteroatom-containing polymers, tellurium-containing polymers exhibit several unique properties and promising applications. However, unlike elements such as boron, silicon, sulfur and so on, tellurium in polymers remains a fresh perspective for many researchers. In this review, we shall illustrate the diversification of tellurium-...
More
Congratulations! Our alumni Dr. Cheng Liu received Jingqing Chemical Spark Award!
Our alumni Dr. Cheng Liu(2017-2022, Ph.D.) received the fourth Jingqing Chemical Spark Award!
Congratulations!
More
Joint Group Meeting between Prof. Huaping Xu’s Group and Prof. Yi Cao’s Group
On March 24th, a joint group meeting was held between Prof. Huaping Xu’s Group from Tsinghua University, Prof. Yi Cao’s Group from Nanjing University and Prof. Fengwei Huo's Group from Nanjing Tech University.
The meeting was chaired by Dr. Ju Guan (Xu' Group) and Dr. Fanchen Meng, consisting of twelve reports totally from three groups.
Mr. Yizheng Tan, Mr. Shuojiong Pan, Mr. Peng Zhao and Mr. Yiheng Dai From our group made the oral presentation respectively.
At the end of the meeting, Prof. Huaping Xu made a summary and outlook.
More
A nanotherapeutic strategy to reverse NK cell exhaustion
Shuojiong Pan, Jun Guan, Banruo Xianyu, Yizheng Tan, Tianyu Li, and Huaping Xu
Adv. Mater.; 2023, 23, 2211370.
As a specialized immune effector cell, natural killer (NK) cells play a very important role in immunotherapy, but tumor immunosuppression caused by abnormal expression of cancer cells seriously weakens its therapeutic effect and leads to exhaustion. Here, we developed a self-assembled selenium containing nanoparticles (NPs) composed of Cetuximab, C5SeSeC5 and inhibitor LY345899 to reverse NK cell exhaustion. The obtained NPs can target EGFR on the surface of cancer cells and locat...
More
Mechanochemistry of dynamic chalcogen-containing polymers: a minireview
Muqing Cao, Yizheng Tan and Huaping Xu
New Journal of Chemistry; 2023, 47, 5582.
In recent years, mechanochemistry of polymers, which means the reactivity of polymers under mechanical stimuli, has been widely studied and greatly developed. Among various kinds of mechano-responsive polymers, dynamic chalcogen-containing polymers have attracted more attention due to their sensitive responsiveness and precise biofunction. In this perspective, we provide an overview of mechanochemistry of dynamic chalcogen-containing polymers, including both fundamental mechanochemistry and applications. Particu...
More
The 4th Table Tennis Tournament of Xu’s Group
On Feb. 12th, 2023, the 4th Table Tennis Tournament of Xu's Group was held in Gas Film Hall, Tsinghua University, with 15 group members joining in.
Mr. Jinyan Si and Mr. Zhuoxin Ge advanced to the final round. And finally, Mr. Jinyan Si won the championship of this year's tournament.
Keep positive in both exercise, work and life!
More
Happy New Year！
Scholarships and prizes of Xu’s group in 2022
Dynamic Fluorescent Patterning Based on Visible-Light-Responsive Diselenide Metathesis
Jinyan Si, Peng Zhao, Jun Guan, Shaobo Ji and Huaping xu
Langmuir; 2022, 38, 13272
A diselenide bond, as a dynamic covalent bond, is a versatile tool to construct smart interfaces, which can respond to visible light. In this work, we used microcontact printing (μCP) to construct diselenide patterns on quartz substrates. Fluorescent patterns were obtained on the modified surfaces via the visible-light-induced diselenide metathesis reaction, which allowed the patterning process to be fast, dynamically erasable, and compatible with different fluorescent molecules including rhodamine B and b...
More