Jiahao Xia, Yizheng Tan, Huaping Xu Acta Polym. Sin.; 2020, 51, 1190. The dynamic covalent bond (DCB) is a kind of special bond that can cleave, reform, and exchange under external stimulus. DCBs have been evolved in a wide range of polymers like self-healing materials, shape memory materials and so on. Selenium is an essential element in human bodies. Our research group pioneered in the research of Se-containing dynamic polymers, and discovered that many Se-containing bonds are dynamic covalent bonds with very mild responsive conditions due to selenium’s unique chemical properties. This f...

Chenxing Sun, Yizheng Tan, Huaping Xu ACS Materials Lett.; 2020, 2, 1173. Nanomaterials are good platforms for the combination of different cancer treatments, such as radiotherapy, chemotherapy, and immunotherapy. However, those materials mostly serve as delivery vehicles for efficient and targeted transport of anticancer drugs. Stimuli-responsive chemical bonds have already been widely applied to construct these nanomaterials for controlled drug release. Diselenide bonds are one example of dual redox responsive bonds. Different from other stimuli-responsive nanomaterials, diselenide- c...

Tianyu Li, Huaping Xu Cell Rep. Phys. Sci.; 2020, 1, 100111. Cancer remains a major global health problem, causing significant economic burden worldwide. Current clinical cancer treatments are unsatisfactory in terms of both antitumor efficacy and biocompatibility. Meanwhile, nanomaterials attract much attention as potential treatment strategies with improved antitumor efficacy and reduced side effects. Selenium-containing nanomaterials are considered to be a promising biomaterial candidate among many different approaches during the last decade. Selenium-containing nanomaterials exhibit go...