Shaobo Ji, Jiahao Xia and Huaping Xu ACS Macro Lett., 2016, 5, 78-82. The application of selenium in the responsive polymer system and the enzyme mimic system have been well studied. Our group initiated this line of research in 2009 by first extending selenium chemistry to dynamic chemistry. In this article, the discovery, progress, and application of selenium-related dynamic covalent bonds will be introduced. The dynamic property of Se–N bond and Se–Se bond were revealed and have been applied in the polymer system as enzyme mimic and self-healing materials, respectively. Further studies...

Wei Cao, Lu Wang and Huaping Xu Nano Today, 2015, 10, 717-736. Selenium/tellurium containing polymers have been attracting growing interest due to their unique properties and potential applications as bio-nanomaterials. The introduction of selenium or tellurium chemistry into block copolymers endows self-assembled nanomaterials with novel stimuli responsiveness and enhanced sensitivity. This review article provides an overview on recent advances of selenium/tellurium containing polymers. We summarize the redox response and reversible self-assembly behaviors, γ-ray responsive systems for ...

Tianyu Li, Mario Smet, Wim Dehaen, and Huaping Xu ACS Appl. Mater. Interfaces, 2016, 8, 3609-3614. Dendrimers are considered as good vectors for drug delivery in cancer treatment. However, most anticancer drugs are conjugated to the peripheral surface of dendrimers, sacrificing the advantages of monodispersity and stability belonging to dendrimers. Furthermore, dendrimers in current studies of cancer treatment are mostly used as vectors for drugs, whereas the anticancer activity of dendrimers on their own is less studied. Here we have prepared monodisperse selenium–platinum coordination ...

Shaobo Ji, Wei Cao, Ying Yu and Huaping Xu Adv. Mater., 2015, 27, 7740-7745. Visible light is an easily achievable and mild trigger for self-healing materials. By incorporating dynamic diselenide bonds into polyurethane, visible-light-induced self-healing materials can be fabricated. Besides mild visible light, the healing process can also be realized using directional laser irradiation, which makes the system a remotely controllable self-healing system.