Lu Wang, Fuqiang Fan, Wei Cao and Huaping Xu
ACS Appl. Mater. Interfaces, 2015, 7, 16054-16060.
Reactive oxygen species (ROS) play a crucial role in cell signaling and redox homeostasis and are strongly related to metabolic activities. The increase of ROS concentration in organisms can result in several diseases, such as cardiovascular diseases and cancer. The concentration of ROS in biologically-relevant conditions is typically as low as around tens of μM to 100 μM H2O2, which makes it necessary to develop ultra-sensitive ROS-responsive systems. A general approach is reported here to fa...
More
Author: wanglu
Mr. Wei Cao participated in the 65th Lindau Nobel Laureate Meeting
Mr. Wei Cao participated in the 65th Lindau Nobel Laureate Meeting, Lindau, Germany as young scientists from June 28 th to July 3 rd, 2015. He was selected as a speaker for the Nobel laureate Prof. Jean-Marie Lehn’s master class on “Supramolecular and Adaptive Chemistry: From Materials Science to Medicine”. The delegation of China was made up of 30 Ph.D. candidates all over the country of different backgrounds including physiology and medicine, chemistry, and physics. After the Lindau Nobel Laureate Meeting, they had a scientific trip around Germany and visited some of the important universiti...
More
Lu Wang’s new work has been accepted by ACS Applied Materials & Interfaces
Congratulations to Lu Wang! Her new work named "Ultra-sensitive ROS-responsive Coassemblies of Tellurium-Containing Molecules and Phospholipids" has been accepted by ACS Applied Materials & Interfaces recently.
More
Prof. Jeremiah A. Johnson visited Tsinghua University and gave a lecture
On Jun. 24th, 2015, prof. Jeremiah A. Johnson from Massachusetts Institute of Technology visited Tsinghua University and gave a lecture about “Using Chemistry to characterize and control polymer structure across length scales” .
More
Ultra-sensitive ROS-responsive Tellurium-containing Polymers
Wei Cao, Yuwei Gu, Tianyu Li and Huaping Xu
Chem. Commun., 2015, 51, 7069-7071.
A novel tellurium-containing polymer micelle system is reported to be responsive to 100 μM H2O2 and can undergo a series of morphological changes. The polymer micelles also respond to 2 Gy gamma radiation, which is the exact dosage a patient receives one day for clinical radiation therapy.
More
Reactive Oxygen Species (ROS)-Responsive Tellurium-Containing Hyperbranched Polymer
Ruochen Fang, Huaping Xu, Wei Cao, Liulin Yang and Xi Zhang
Polym. Chem., 2015, 6, 2817-2821.
Materials responsive to reactive oxygen species (ROS) at a physiological level are of great significance in diagnostic and therapeutic applications. We have synthesized a water-soluble tellurium-containing hyperbranched polymer and demonstrated that it forms a kind of ROS-responsive aggregate. In aqueous environment, the polymer aggregates can swell under biologically relevant concentration of H2O2, which could be expected to find applications in fields such as elimination of excess ROS.
More
Prof. You Han Bae visited Tsinghua University and gave a lecture
Prof. You Han Bae from University of Utah visited Tsinghua University and gave a lecture about “Current Paradigm of Therapeutic Cancer Nanomedicine and Its Prospective: A gap between Preclinical and Clinical Outcomes” on Mar. 16th, 2015.
More
Congratulations! Tianyu Li received “Best Young Researchers” oral presentation award in 2015 Nano Med Conference
Tianyu Li gave a 2 min oral presentation and a poster presentation of “EGSe/Pt selectively kill cancer cells via ROS” on the 1st International Symposium on Translational Nanomedicine, Guangzhou, China from Jan.8th to Jan.10th, 2015. He got the award for “Best Young Researchers” presented by the committee of NanoMed 2015.
More
Dr. Wenxin Wang visited Tsinghua University and gave a lecture
Dr. Wenxin Wang from University College Dublin, Ireland visited Tsinghua University and gave a lecture about "Controlled Multivinyl Monomer Polymerization" on Jan. 20th, 2015.
More
